Today we celebrate the publication of the human genome with an image of the super helix. On 15th February 2001 researchers published the first sequence-based map of large-scale structural variation across the human genome in the journal Nature. Large-scale structural variations are differences in the genome among people that range from a few thousand to a few million DNA bases; some are gains or losses of stretches of genome sequence and others appear as re-arrangements of stretches of sequence. These variations include differences in the number of copies individuals have of a particular gene, deletions, translocations, and inversions…
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